How does Lorlatinib 100 mg tablet work?

[magicinepharma]

It is an anti-cancer medicine used primarily to treat non-small cell lung cancer. It contain kinase inhibitor which blocks the action of protein response to the multiplication of cancer cells. Side effects associated with the medicine includes breathlessness, diarrhea, joint pain, high blood pressure, edema, weight gain, and high cholesterol. The prescribed dosage is usually one tablet daily as per recommendation but one must consult with doctor before taking the medicine.
For more Info -Lorlatinib 100 mg tablet

[Karer09334]

Lorlatinib is a medication used in the treatment of certain types of cancer, specifically non-small cell lung cancer (NSCLC) that carries certain genetic mutations, such as ALK or ROS1 rearrangements. It is available in tablet form, including the 100 mg strength.

Lorlatinib belongs to a class of drugs called tyrosine kinase inhibitors (TKIs). It works by targeting and inhibiting specific proteins called ALK and ROS1 tyrosine kinases, which are abnormal proteins found in some cancer cells. These proteins play a role in promoting the growth and survival of cancer cells.

By blocking the activity of ALK and ROS1 tyrosine kinases, lorlatinib helps to inhibit the signaling pathways that contribute to cancer cell growth and proliferation. It can also penetrate the blood-brain barrier, making it effective in treating metastatic NSCLC that has spread to the brain.

Lorlatinib's ability to target ALK and ROS1 mutations makes it particularly effective in patients whose cancer has developed resistance to other ALK inhibitors. It has shown promising results in clinical trials, including shrinking tumors and extending progression-free survival in patients with ALK-positive NSCLC.

It's important to note that lorlatinib should only be used under the supervision of a healthcare professional who is experienced in the treatment of cancer. They will consider the specific genetic mutation, stage of cancer, and individual patient factors to determine the appropriate dosage and treatment plan.